11janvier2019

Metabolism before enzymes ?

Salle de conférence Léon Hirth - 9h15

Prof Joseph MORAN, Laboratory of Chemical Catalysis at ISIS, University of Strasbourg & CNRS - invité par H. Renault

Joseph Moran is Professor of chemistry at the University of Strasbourg and head of the Laboratoire de Catalyse Chimique at the Institut de Science et d’Ingénierie Supramoléculaires (ISIS). His group investigates the origins of life chemical pathways and how they could have emerged at a time enzymes were absent. Among other discoveries, Joseph Moran’s group showed that transition metals can serve as versatile catalysts for reverse Krebs cycle functioning and CO2 fixation. This breakthroughs shed light on the origins of metabolism, pointing to a prebiotic chemistry that eventually paved the way to the emergence of the complex biochemistry as we experience it today.