Pascal GENSCHIK

Ses publications

  • INCARBONE M., CLAVEL M., MONSION B., KUHN L., SCHEER H., VANTARD E., POIGNAVENT V., DUNOYER P., GENSCHIK P. and RITZENTHALER C.

    Immunocapture of dsRNA-bound proteins provides insight into Tobacco rattle virus replication complexes and reveals Arabidopsis DRB2 to be a wide-spectrum antiviral effector

    Plant Cell, 1, 2021.

  • GENTRIC N., GENSCHIK P. and NOIR S.

    Connections between the Cell Cycle and the DNA Damage Response in Plants

    International Journal of Molecular Sciences, 9558, 2021. | DOI : https://doi.org/10.3390/ijms22179558DOI logo

  • CLAVEL M., LECHNER E., INCARBONE M., VINCENT T., COGNAT V., SMIRNOVA E., LECORBEILLER M., BRAULT V., ZIEGLER-GRAFF V. and GENSCHIK P.

    Atypical molecular features of RNA silencing against the phloem-restricted polerovirus TuYV

    Nucleic Acid Research, in press, 2021. | DOI : 10.1093/nar/gkab802DOI logo

  • GENTRIC N., MASOUD K., JOURNOT R.P., COGNAT V., CHABOUTÉ M.E., NOIR S. and GENSCHIK P.

    The F-box-like protein FBL17 is a regulator of DNA-damage response and co-localizes with RETINOBLASTOMA RELATED 1 at DNA lesion sites

    Plant Physiology, 20.00188, 2020. | DOI : https://doi.org/10.1104/pp.20.00188DOI logo

  • POTUSCHAK T., PALATNIK J., SCHOMMER C., SIERRO N., IVANO N., KWON Y., GENSCHIK P., DAVIÈRE J.M. and OTTEN L.

    Inhibition of Arabidopsis thaliana CIN-like TCP transcription factors by Agrobacterium T-DNA-encoded 6B proteins.

    Plant Journal, 1303-1317, 2020. | DOI : doi: 10.1111/tpj.14591DOI logo

  • CHICO J.M., LECHNER E., FERNANDEZ-BARBERO G., CANIBANO E., GARCÍA-CASADO G., FRANCO-ZORRILLA J.M., HAMMANN P., ZAMARREÑO A.M., GARCÍA-MINA J.M., RUBIO V., GENSCHIK P. and SOLANO R.

    CUL3 BPM E3 ubiquitin ligases regulate MYC2, MYC3, and MYC4 stability and JA responses

    Proceedings of the National Academy of Sciences of the United States of America, 6205-6215, 2020. | DOI : 10.1073/pnas.1912199117DOI logo

  • OROSA B., ÜSTÜN S., CALDERÓN VILLALOBOS L.I.A., GENSCHIK P., GIBBS D., HOLDSWORTH M.J., ISONO E., LOIS M., TRUJILLO M. and SADANANDOM A.

    Plant proteostasis - shaping the proteome: a research community aiming to understand molecular mechanisms that control protein abundance

    New Phytologist, , 2020.

  • MICHAELI S., CLAVEL M., LECHNER E., VIOTTI C., WU J., DUBOIS M., HACQUARD T., DERRIEN B., IZQUIERDO E., LECORBEILLER M., BOUTEILLER N., DE CILIA J., ZIEGLER-GRAFF V., VAUCHERET H., GALILI G. and GENSCHIK P.

    The viral F-box protein P0 induces an ER-derived autophagy degradation pathway for the clearance of membrane-bound AGO1

    Proceedings of the National Academy of Sciences of the United States of America, 116(45):22872-22883, 2019. | DOI : 10.1073/pnas.1912222116DOI logo

  • JULIAN J., COEGO A., LOZANO-JUSTE J., LECHNER E., WU Q., ZHANG X., MERILO E., BELDA-PALAZON B., PARK S.Y., CUTLER S.R., AN C., GENSCHIK P. and RODRIGUEZ P.L.

    The MATH-BTB BPM3 and BPM5 subunits of Cullin3-RING E3 ubiquitin ligases target PP2CA and other clade A PP2Cs for degradation

    Proceedings of the National Academy of Sciences of the United States of America, 15725-15734, 2019. | DOI : 10.1073/pnas.1908677116DOI logo

  • TROLET A., BALDRICH P., CRIQUI M.C., DUBOIS M., CLAVEL M., MEYERS B.C. and GENSCHIK P.

    Cell Cycle-Dependent Regulation and Function of ARGONAUTE1 in Plants

    Plant Cell, 1734-1750, 2019. | DOI : 10.1105/tpc.19.00069DOI logo

  • ŠKILJAICA A., LECHNER E., JAGIĆ M., MAJSEC K., MALENICA N., GENSCHIK P. and BAUER N.

    The protein turnover of Arabidopsis BPM1 is involved in regulation of flowering time and abiotic stress response

    Plant Molecular Biology, , 2019.

  • GENSCHIK P.

    RPN10: A Case Study for Ubiquitin Binding Proteins and More

    Plant Cell, , 2019.

  • VASEVA I., QUDEIMAT E., POTUSCHAK T., DU Y., GENSCHIK P., VANDENBUSSCHE F. and VAN DER STRAETEN D.

    The plant hormone ethylene restricts Arabidopsis growth via the epidermis

    Proceedings of the National Academy of Sciences of the United States of America, E4130-E4139, 2018. | DOI : 10.1073/pnas.1717649115DOI logo

  • DERRIEN B., CLAVEL M., BAUMBERGER N., IKI T., SARAZIN A., HACQUARD T., ZIEGLER-GRAFF V., VAUCHERET H., MICOL J.L., VOINNET O. and GENSCHIK P.

    A Suppressor Screen for AGO1 Degradation by the Viral F-Box P0 Protein Uncovers a Role for AGO DUF1785 in sRNA Duplex Unwinding.

    Plant Cell, 1353-1374., 2018. | DOI : 10.1105/tpc.18.00111DOI logo

  • DUBOIS M., SELDEN K., BEDIEE A., ROLLAND G., BAUMBERGER N., NOIR S., BACH L., LAMY G., GRANIER C. and GENSCHIK P.

    SIAMESE-RELATED1 Is Regulated Posttranslationally and Participates in Repression of Leaf Growth under Moderate Drought.

    Plant Physiology, 2834-2850, 2018.

  • POTUSCHAK T. and GENSCHIK P.

    Dark night, cold ground

    Nature Plants, 3(11):846-847, 2017. | DOI : 10.1038/s41477-017-0043-3DOI logo

  • CLAVEL M., MICHAELI S. and GENSCHIK P.

    Autophagy: A Double-Edged Sword to Fight Plant Viruses.

    Trends in Plant Science, 646-648, 2017. | DOI : 10.1016/j.tplants.2017.06.007DOI logo

  • MICHAELI S., GALILI G., GENSCHIK P., FERNIE A. and AVIN-WITTENBERG T.

    Autophagy in Plants--What's New on the Menu?

    Trends in Plant Science, 134-44, 2016. | DOI : 10.1016DOI logo

  • SCHALK C., DREVENSEK S., KRAMDI A., KASSAM M., AHMED I., COGNAT V., GRAINDORGE S., BERGDOLL M., BAUMBERGER N., HEINTZ D., BOWLER C., GENSCHIK P., BARNECHE F., COLOT V. and MOLINIER J.

    DNA DAMAGE BINDING PROTEIN 2 (DDB2) Shapes the DNA Methylation Landscape

    Plant Cell, 28:2043-2059, 2016. | DOI : 10.1105/tpc.16.00474DOI logo

  • NOIR S., MARROCCO K., HLEIBIEH K., THOMANN A., GUSTI A., BITRIAN M., SCHNITTGER A. and GENSCHIK P.

    The Control of Arabidopsis thaliana Growth by Cell Proliferation and Endoreplication Requires the F-Box Protein FBL17.

    Plant Cell, 27:1461-1476, 2015. | DOI : 10.1105/tpc.114.135301DOI logo

  • DAVIÈRE J.M., WILD M., REGNAULT T., BAUMBERGER N., EISLER H., GENSCHIK P. and ACHARD P.

    Class I TCP-DELLA interactions in inflorescence shoot apex determine plant height

    Current Biology, 24(16):1923-8, 2014. | DOI : 10.1016/j.cub.2014.07.012DOI logo

  • GENSCHIK P., MARROCCO K., BACH L., NOIR S. and CRIQUI M.C.

    Selective protein degradation: a rheostat to modulate cell-cycle phase transitions.

    Journal of Experimental Botany, 65(10):2603-2615, 2014. | DOI : 10.1093/jxb/ert426DOI logo

  • DERRIEN B. and GENSCHIK P.

    When RNA and protein degradation pathways meet

    Frontiers in Plant Science, 5(23):161, 2014. | DOI : 10.3389/fpls.2014.00161DOI logo

  • FU H., GORING D.R. and GENSCHIK P.

    Reversible ubiquitylation in plant biology

    Frontiers in Plant Science, , 2014.

  • TROMAS A., PAQUE S., STIERLÉ V., QUETTIER A.L., MULLER P., LECHNER E., GENSCHIK P. and PERROT-RECHENMANN C.

    Auxin-Binding Protein 1 is a negative regulator of the SCF(TIR1/AFB) pathway.

    Nature Communications, 4(2496):doi:10.1038/ncomms3496, 2013. | DOI : 10.1038/ncomms3496DOI logo

  • GENSCHIK P., SUMARA I. and LECHNER E.

    The emerging family of CULLIN3-RING ligases (CRL3s) : cellular functions and disease implications .

    EMBO Journal, 32:2307-2320, 2013. | DOI : 10.1038/emboj.2013.173DOI logo

  • DERRIEN B., BAUMBERGER N., SCHEPETILNIKOV M., VIOTTI C., DE CILLIA J., ZIEGLER-GRAFF V., ISONO E., SCHUMACHER K. and GENSCHIK P.

    Degradation of the antiviral component ARGONAUTE1 by the autophagy pathway

    Proceedings of the National Academy of Sciences of the United States of America, 109(39):15942-15946, 2012. | DOI : 10.1073/pnas.1209487109DOI logo

  • WILD M., DAVIÈRE J.M., CHEMINANT S., REGNAULT T., BAUMBERGER N., HEINTZ D., BALTZ R., GENSCHIK P. and ACHARD P.

    The Arabidopsis DELLA RGA-LIKE3 Is a Direct Target of MYC2 and Modulates Jasmonate Signaling Responses

    Plant Cell, 24:3307-3319, 2012. | DOI : 10.1105/tpc.112.101428DOI logo

  • BJERKAN K.N., JUNG-ROMÉO S., JÜRGENS G., GENSCHIK P. and GRINI P.E.

    Arabidopsis WD REPEAT DOMAIN55 Interacts with DNA DAMAGED BINDING PROTEIN1 and Is Required for Apical Patterning in the Embryo.

    Plant Cell, 24(3):1013-33, 2012. | DOI : 10.1105/tpc.111.089425DOI logo

  • MARROCCO K., CRIQUI M.C., ZERVUDACKI J., SCHOTT G., EISLER H., PARNET A., DUNOYER P. and GENSCHIK P.

    APC/C-mediated degradation of dsRNA-binding protein 4 (DRB4) involved in RNA silencing

    PLoS ONE, 7(4):e35173, 2012. | DOI : 10.1371/journal.pone.0035173DOI logo

  • IWATA E., IKEDA S., ABE N., KOBAYASHI A., KURATA M., MATSUNAGA S., YOSHIOKA Y., CRIQUI M.C., GENSCHIK P. and ITO M.

    Roles of GIG1 and UVI4 in genome duplication in Arabidopsis thaliana

    Plant Signaling and Behavior, 7(9):1079-1981, 2012. | DOI : 10.4161/psb.21133DOI logo

  • CASTELLS E., MOLINIER J., BENVENUTO G., BOURBOUSSE C., ZABULON G., ZALC A., CAZZANIGA S., GENSCHIK P., BARNECHE F. and BOWLER C.

    The conserved factor DE-ETIOLATED 1 cooperates with CUL4-DDB1DDB2 to maintain genome integrity upon UV stress

    EMBO Journal, 30:1162-1172, 2011. | DOI : 10.1038/emboj.2011.20DOI logo

  • DUMBLIAUSKAS E., LECHNER E., JACIUBEK M., BERR A., PAZHOUHANDEH M., ALIOUA A., COGNAT V., BRUKHIN V., KONCZ C., GROSSNIKLAUS U., MOLINIER J. and GENSCHIK P.

    The Arabidopsis CUL4-DDB1 complex interacts with MSI1 and is required to maintain MEDEA parental imprinting

    EMBO Journal, 30:731-743, 2011. | DOI : 10.1038/emboj.2010.359DOI logo

  • PAZHOUHANDEH M., MOLINIER J., BERR A. and GENSCHIK P.

    MSI4/FVE interacts with CUL4-DDB1 and a PRC2-like complex to control epigenetic regulation of flowering time in Arabidopsis

    Proceedings of the National Academy of Sciences of the United States of America, 108(8):3430-3435, 2011. | DOI : 10.1073/pnas.1018242108DOI logo

  • SASABE M., BOUDOLF V., DE VEYLDER L., INZÉ D., GENSCHIK P. and MACHIDA Y.

    Phosphorylation of a mitotic kinesin-like protein and a MAPKKK by cyclin-dependent kinases (CDKs) is involved in the transition to cytokinesis in plants.

    Proceedings of the National Academy of Sciences of the United States of America, 108(43):17844-17849, 2011. | DOI : 10.1073/pnas.1110174108DOI logo

  • LECHNER E., LEONHARDT N., EISLER H., PARMENTIER Y., ALIOUA A., JACQUET H., LEUNG J. and GENSCHIK P.

    MATH/BTB CRL3 receptors target the homeodomain-leucine zipper ATHB6 to modulate abscisic acid signalling.

    Developmental Cell, 13:1116-1128, 2011. | DOI : 10.1016/j.devcel.2011.10.018DOI logo

  • LINGAM S., MOHRBACHER J., BRUMBAROVA T., POTUSCHAK T., FINK-STRAUBE C., BLONDET E., GENSCHIK P. and BAUER P.

    Interaction between the bHLH transcription factor FIT and Ethylene insensitive3/ethylene insensitive3-like1 reveals molecular linkage between the regulation of iron acquisition and ethylene signaling in Arabidopsis

    Plant Cell, 23:1815-1829, 2011. | DOI : 10.1105/tpc.111.084715DOI logo

  • CHEMINANT S., WILD M., BOUVIER F., PELLETIER S., RENOU J.P., ERHARDT M., HAYES S., TERRY M.J., GENSCHIK P. and ACHARD P.

    DELLAs regulate chlorophyll and carotenoid biosynthesis to prevent photo-oxidative damage during seedling deeliolation

    Plant Cell, 23:1849-1860, 2011. | DOI : 10.1105/tpc.111.085233DOI logo

  • ROBERTS D., PEDMALE U.V., MORROW J., SACHDEV S., LECHNER E., TANG X., ZHENG N., HANNINK M., GENSCHIK P. and LISCUM E.

    Modulation of phototropic responsiveness in Arabidopsis through ubiquitination of phototropin 1 by the CUL3-ring E3 ubiquitin ligase CRL3 NPH3.

    Plant Cell, 23:3627-3640, 2011. | DOI : 10.1105/tpc.111.087999DOI logo

  • IWATA E., IKEDA S., MATSUNAGA S., KURATA M., YOSHIOKA Y., CRIQUI M.C., GENSCHIK P. and ITO M.

    GIGAS CELL 1, a novel negative regulator of the Anaphase-Promoting Complex/Cyclosome, is required for proper mitotic progression and cell fate determination in Arabidopsis

    Plant Cell, 23:4382-4393, 2011. | DOI : 10.1105/tpc.111.092049DOI logo

  • CASTELLS E., MOLINIER J., DREVENSEK S., GENSCHIK P., BARNECHE F. and BOWLER C.

    det1-1-induced UV-C hyposensitivity through UVR3 and PHR1 photolyase gene over-expression

    Plant Journal, 63:392-404, 2010.

  • MARROCCO K., BERGDOLL M., ACHARD P., CRIQUI M.C. and GENSCHIK P.

    Selective proteolysis sets the tempo of the cell cycle

    Current Opinion in Plant Biology, 631-9, 2010.

  • ROODBARKELARI F., BRAMSIEPE J., WEINL C., MARQUARDT S., NOVÁK B., AKOBY M.J.J., LECHNER E., GENSCHIK P. and SCHNITTGER A.

    Cullin 4-ring finger-ligase plays a key role in the control of endoreplication cycles in Arabidopsis trichomes

    Proceedings of the National Academy of Sciences of the United States of America, 15275-80, 2010. | DOI : 10.1073/pnas.1006941107DOI logo

  • ACHARD P., GUSTI A., CHEMINANT S., ALIOUA A., DHONDT S., COPPENS F., BEEMSTER G. and GENSCHIK P.

    Gibberellin signaling controls cell proliferation in Arabidopsis

    Current Biology, 19:1188-1193, 2009. | DOI : 10.1016/j.cub.2009.05.059DOI logo

  • SPOEL S.H., MOU Z., TADA Y., SPIVEY N.W., GENSCHIK P. and DONG X.

    Proteasome-mediated turnover of the transcription coactivator NPR1 plays dual roles in regulating plant immunity

    Cell, 860-72, 2009. | DOI : 10.1016/j.cell.2009.03.038DOI logo

  • MARROCCO K., THOMANN A., PARMENTIER Y., GENSCHIK P. and CRIQUI M.C.

    The APC/C E3 ligase remains active in most post-mitotic Arabidopsis cells and is required for proper vasculature development and organization

    Development, 1475-85, 2009. | DOI : 10.1242/dev.035535DOI logo

  • GUSTI A., BAUMBERGER N., NOWACK M., PUSCH S., EISLER H., POTUSCHAK T., DE VEYLDER L., SCHNITTGER A. and GENSCHIK P.

    The Arabidopsis thaliana F-box protein FBL17 is essential for progression through the second mitosis during pollen development

    PLoS ONE, 4(3):e4780, 2009. | DOI : 10.1371/journal.pone.0004780DOI logo

  • KATO K., GÁLIS I., SUZUKI S., ARAKI S., DEMURA T., CRIQUI M.C., POTUSCHAK T., GENSCHIK P., FUKUDA H., MATSUOKA K. and ITO M.

    Preferential up-regulation of G2/M phase-specific genes by overexpression of the hyperactive form of NtmybA2 lacking its negative regulation domain in tobacco BY-2 cells

    Plant Physiology, 1945-57, 2009. | DOI : 10.1104/pp.109.135582DOI logo

  • STUTTMA J., LECHNER E., GUÉROIS R., PARKER J.E., NUSSAUME L., GENSCHIK P. and NOËL L.D.

    COP9 signalosome- and 26S proteasome-dependent regulation of SCFTIR1 accumulation in Arabidopsis

    Journal of Biological Chemistry, 7920-30, 2009. | DOI : 10.1074/jbc.M809069200DOI logo

  • THOMANN A., LECHNER E., HANSEN M., DUMBLIAUSKAS E., PARMENTIER Y., KIEBER J., SCHERES B. and GENSCHIK P.

    Arabidopsis CULLIN3 genes regulate primary root growth and patterning by ethylene-dependent and -independent mechanisms

    PLoS Genetics, 5(1):e1000328, 2009. | DOI : 10.1371/journal.pgen.1000328DOI logo

  • ACHARD P. and GENSCHIK P.

    Releasing the brakes of plant growth: how GAs shutdown DELLA proteins.

    Journal of Experimental Botany, 1085-92, 2009. | DOI : 10.1093/jxb/ern301DOI logo

  • ACHARD P., RENOU J., BERTHOMÉ R., HARBERD N. and GENSCHIK P.

    Plant DELLAs restrain growth and promote survival of adversity by reducing the levels of reactive oxygen species.

    Current Biology, 18:656-60, 2008. | DOI : 10.1016/j.cub.2008.04.034DOI logo

  • MOLINIER J., LECHNER E., DUMBLIAUSKAS E. and GENSCHIK P.

    Regulation and role of Arabidopsis CUL4-DDB1A-DDB2 in maintaining genome integrity upon UV stress

    PLoS Genetics, 6: e1000093, 2008.

  • ACHARD P., GONG F., CHEMINANT S., ALIOUA A., HEDDEN P. and GENSCHIK P.

    The cold-inducible CBF1 factor-dependent signaling pathway modulates the accumulation of the growth-repressing DELLA proteins via its effect on gibberellin metabolism

    Plant Cell, 10.1105/tpc.108.058941, 2008. | DOI : 10.1105/tpc.108.058941DOI logo

  • PÉREZ-PÉREZ J.M., SERRALBO O., VANSTRAELEN M., GONZÁLEZ C., CRIQUI M.C., GENSCHIK P., KONDOROSI E. and SCHERES B.

    Specialization of CDC27 function in the Arabidopsis thaliana anaphase-promoting complex (APC/C)

    Plant Journal, 78-89, 2008. | DOI : 10.1111/j.1365-313X.2007.03312.xDOI logo