Transfer RNAs (tRNAs) play a key role in the translation and reading of the genetic code. Therefore, the regulation of the expression of their genes must be perfectly orchestrated. In this study, published online September 17 in the journal Nucleic Acids Research, two IBMP teams demonstrated the importance of the genomic and epigenomic environment for the transcription of nuclear tRNA genes in plants.
Figure © Jean Molinier & Laurence Drouard
Legende : The tRNA (t-DNA) genes scattered on Arabidopsis chromosomes are expressed, those that are clustered are methylated and remain silent.