Resetting ABA signaling requires the degradation of PP2C phosphatases by BPM3 and 5 proteins

As sessile organisms, plants need fast, finely regulated signaling pathways to adapt their growth and survival to their immediate and often adverse environment. For the responses to biotic and abiotic stresses, abscisic acid (ABA), in particular, is a crucial phytohormone. In this study, researchers highlighted the role of BTB / POZ AND MATH DOMAIN (BPM) proteins as a regulator in the ABA signaling pathway: Arabidopsis BPM3 and 5 proteins target PP2C phosphatases for degradation. class A essential for the transmission of the ABA signal. This selective degradation reaction of PP2C proteins is a key step in the desensitization and resetting mechanism of the ABA signal. This work, the fruit of international collaboration, was published in PNAS on July 15, 2019.