Microscopy and cellular imaging

Leader: Mathieu ERHARDT

Description

The microscopy facility was the first technology platform established in the IBMP in 1998. It’s scientific programme aims at understanding the expression of plant or animal genes over space and time at various levels. Microorganisms or biomaterials studied by partner research units are other topics of interest. Our facility follows official guidelines for « Plates-Formes Technologiques du Vivant » and has received RIO 2001, 2004 and 2006 labels. It’s part of the larger Strasbourg Esplanade Cell Imaging Facility that allows sharing devices and knowledge from 7 research units from CNRS, INSERM, UNISTRA and INRA.

Missions

  • Assist research from IBMP and partner research units
  • Develop and implement new imaging technologies
  • Give appropriate one-to-one or group training to research staff
  • Get involved in microscopy education and science popularization
  • Make sure our devices are up and running

Expertises

Electron Microscopy and histology

Manager : Mathieu ERHARDT

Provides expertise, development and training for the following technologies:

  • TEM, SEM, serial block face imaging
  • Histology, cytology, in situ hybridization

Optical microscopy and bioimage analysis

Manager : Jérôme MUTTERER

Provides expertise, development and training for the following technologies:

  • Brightfield , fluorescence, confocal microscopy, fluorescence lifetime imaging
  • Image Processing

Members

Recent publications

  • VILLETTE C., MAURER L., DELECOLLE J., ZUMSTEG J., ERHARDT M. and HEINTZ D.

    In situ localization of micropollutants and associated stress response in Populus nigra leaves

    Environment International, 126:523-532, 2019. | DOI : https://www.ncbi.nlm.nih.gov/pubmed/30851483DOI logo

  • GAMPER C., SPENLÉ C., BOSCÁ S., VAN DER HEYDEN M., ERHARDT M., OREND G., BAGNARD D. and HEINLEIN M.

    Functionalized Tobacco mosaic virus Coat Protein Monomers and Oligomers as Nanocarriers for Anti-Cancer Peptides

    Cancers, 11:1609, 2019. | DOI : 10.3390/cancers11101609DOI logo

  • GRAINDORGE S., COGNAT V., JOHANN TO BERENS P., MUTTERER J. and MOLINIER J.

    Photodamage repair pathways contribute to the accurate maintenance of the DNA methylome landscape upon UV exposure

    PLoS Genetics, 15(11):e1008476, 2019. | DOI : 10.1371/journal.pgen.1008476DOI logo

  • CHICOIS C., SCHEER H., GARCIA S., ZUBER H., MUTTERER J., CHICHER J., HAMMANN P., GAGLIARDI D. and GARCIA D.

    The UPF1 interactome reveals interaction networks between RNA degradation and translation repression factors in Arabidopsis

    Plant Journal, 96:119-132, 2018. | DOI : 10.1111/tpj.14022DOI logo

  • KØRNER C.J., PITZALIS N., PEÑA E.J., ERHARDT M., VAZQUEZ F. and HEINLEIN M.

    Crosstalk between PTGS and TGS pathways in natural antiviral immunity and disease recovery

    Nature Plants, 4:157-164, 2018. | DOI : 10.1038/s41477-018-0117-xDOI logo