FRIENDLY (FMT), an RNA binding protein associated with cytosolic ribosomes at the mitochondrial surface

Intracellular trafficking of mRNAs and localized protein synthesis are fundamental mechanisms for controlling protein localization. Recent data have revealed selective translation of mRNAs at the surface of mitochondria. Indeed, one-third of mRNAs coding for nuclear-encoded mitochondrial proteins were found at the surface of plant mitochondria.

In a study published in The Plant Journal, scientists from Anne-Marie Duchêne‘s team showed that FRIENDLY (FMT) is the first plant RNA-binding protein identified to participate in the localization of mRNAs and their translation at the surface of mitochondria.