Wen Hui SHEN

Directeur de recherche / Research director

Publications

  • CHEN K., DU K., SHI Y., YIN L., SHEN W.H., YU Y., LIU B. and DONG A.

    H3K36 methyltransferase SDG708 enhances drought tolerance by promoting abscisic acid biosynthesis in rice

    New Phytologist, 230:1967-1984, 2021. | DOI : 10.1111/nph.17290DOI logo

  • GUO Z., LI Z., LIU Y., AN Z., PENG M., SHEN W.H., DONG A. and YU Y.

    MRG1/2 histone methylation readers and HD2C histone deacetylase associate in repression of the florigen gene FT to set a proper flowering time in response to day-length changes

    New Phytologist, 227:1453-1466, 2020. | DOI : 10.1111/nph.16616DOI logo

  • AN Z., YIN L., LIU Y., PENG M., SHEN W.H. and DONG A.

    The histone methylation readers MRG1/MRG2 and the histone chaperones NRP1/NRP2 associate in fine-tuning Arabidopsis flowering time

    Plant Journal, 103:1010-1024, 2020. | DOI : 10.1111/tpj.14780DOI logo

  • ZHANG X., MENARD R., LI Y., CORUZZI G., HEITZ T., SHEN W.H. and BERR A.

    Arabidopsis SDG8 Potentiates the Sustainable Transcriptional Induction of the Pathogenesis-Related Genes PR1 and PR2 During Plant Defense Response

    Frontiers in Plant Science, 11:277, 2020. | DOI : 10.3389/fpls.2020.00277DOI logo

  • DU K., LUO Q., YIN L., WU J., LIU Y., GAN J., DONG A. and SHEN W.H.

    OsChz1 acts as a histone chaperone in modulating chromatin organization and genome function in rice

    Nature Communications, 11(1):5717, 2020. | DOI : 10.1038/s41467-020-19586-zDOI logo

  • LUO Q., WANG B., WU Z., JIANG W., WANG Y., DU K., ZHOU N., ZHENG L., GAN J., SHEN W.H., MA J. and DONG A.

    NAP1-RELATED PROTEIN1 (NRP1) has multiple interaction modes for chaperoning histones H2A-H2B

    Proceedings of the National Academy of Sciences of the United States of America, 117:30391-30399, 2020. | DOI : 10.1073/pnas.2011089117DOI logo

  • YANG C., YIN L., XIE F., MA M., HUANG S., ZENG Y., SHEN W.H., DONG A. and LI L.

    AtINO80 represses photomorphogenesis by modulating nucleosome density and H2A.Z incorporation in light-related genes

    Proceedings of the National Academy of Sciences of the United States of America, 117(52):33679-33688, 2020. | DOI : 10.1073/pnas.2001976117DOI logo

  • ZHAO W., NEYT P., VAN LIJSEBETTENS M., SHEN W.H. and BERR A.

    Interactive and non-interactive roles of histone H2B monoubiquitination and H3K36 methylation in the regulation of active gene transcription and control of plant growth and development

    New Phytologist, 221:1101-1116, 2019. | DOI : 10.1111/nph.15418DOI logo

  • JIANG W., LI Z., YAO X., ZHENG B., SHEN W.H. and DONG A.

    jaw-1D: a gain-of-function mutation responsive to paramutation-like induction of epigenetic silencing

    Journal of Experimental Botany, 70(2):459-468, 2019. | DOI : 10.1093/jxb/ery365DOI logo

  • KANG H., MA J., WU D., SHEN W.H. and ZHU Y.

    Functional coordination of the chromatin-remodeling factor AtINO80 and the histone chaperones NRP1/2 in inflorescence meristem and root apical meristem

    Frontiers in Plant Science, 10:115, 2019. | DOI : 10.3389/fpls.2019.00115DOI logo

  • KANG H., ZHANG C., AN Z., SHEN W.H. and ZHU Y.

    AtINO80 and AtARP5 physically interact and play common as well as distinct roles in regulating plant growth and development

    New Phytologist, 223:336-353, 2019. | DOI : 10.1111/nph.15780DOI logo

  • LIU B., LIU Y., WANG B., LUO Q., SHI J., GAN J., SHEN W.H., YU Y. and DONG A.

    The transcription factor OsSUF4 interacts with SDG725 in promoting H3K36me3 establishment

    Nature Communications, 10:2999, 2019. | DOI : 10.1038/s41467-019-10850-5DOI logo

  • LIU Y., LIU K., YIN L., YU Y., QI J., SHEN W.H., ZHU J., ZHANG Y. and DONG A.

    H4K4me2 functions as a repressive epigenetic mark in plants

    Epigenetics & Chromatin, 12:40, 2019. | DOI : 10.1186/s13072-019-0285-6DOI logo

  • HUANG Y., JIANG L., LIU B.Y., TAN C.F., CHEN D.H., SHEN W.H. and RUAN Y.

    Evolution and conservation of Polycomb Repressive Complex 1 core components and putative associated factors in the green lineage

    BMC Genomics, 20:533, 2019. | DOI : 10.1186/s12864-019-5905-9DOI logo

  • CHEN D.H., WANG Q., FENG J., RUAN Y. and SHEN W.H.

    Arabidopsis ZUOTIN RELATED FACTOR1 Proteins Are Required for Proper Embryonic and Post-Embryonic Root Development

    Frontiers in Plant Science, 10:1498, 2019. | DOI : doi.org/10.3389/fpls.2019.01498DOI logo

  • PENG M., LI Z., ZHOU N., MA M., JIANG Y., DONG A., SHEN W.H. and LI L.

    Linking PHYTOCHROME-INTERACTING FACTOR to histone modification in plant shade avoidance

    Plant Physiology, 176:1341-1351, 2018. | DOI : 10.1104/pp.17.01189DOI logo

  • JIANG L., LI D., JIN L., RUAN Y., SHEN W.H. and LIU C.

    Histone lysine methyltransferases BnaSDG8.A and BnaSDG8.C are involved in the floral transition in Brassica napus

    Plant Journal, 95:672-685, 2018. | DOI : 10.1111/tpj.13978DOI logo

  • MA J., LIU Y., ZHOU W., ZHU Y., DONG A. and SHEN W.H.

    Histone chaperones play crucial roles in maintenance of stem cell niche during plant root development

    Plant Journal, 95:86-100, 2018. | DOI : 10.1111/tpj.13933DOI logo

  • PENG L., WANG L., ZHANG Y., DONG A., SHEN W.H. and HUANG Y.

    Structural analysis of the Arabidopsis AL2-PAL and PRC1 complex provides mechanistic insight about active-to-repressive chromatin state switch

    Journal of Molecular Biology, 430:4245-4259, 2018. | DOI : 10.1016/j.jmb.2018.08.021DOI logo

  • LI C., LIU Y., SHEN W.H., YU Y. and DONG A.

    Chromatin-remodeling factor OsINO80 is involved in regulation of gibberellin biosynthesis and is crucial for rice plant growth and development

    Journal of Integrative Plant Biology, 60:144-159, 2018. | DOI : 10.1111/jipb.12603DOI logo

  • WANG Q. and SHEN W.H.

    Chromatin Modulation and Gene Regulation in Plants: Insight about PRC1 Function

    Biochemical Society Transactions, 46:957-966, 2018. | DOI : 10.1042/BST20170576DOI logo

  • ZHU Y., RONG L., LUO Q., WANG B., ZHOU N., YANG Y., ZHANG C., FENG H., ZHENG L., SHEN W.H., MA J. and DONG A.

    The Histone Chaperone NRP1 Interactsd with WEREWOLF to Activate GLABRA2 in Arabidopsis Root Hair Development

    Plant Cell, 29:260-276, 2017. | DOI : 10.1105/tpc.16.00719DOI logo

  • LIU K., YU Y., DONG A. and SHEN W.H.

    SET DOMAIN GROUP701 encodes a H3K4-methytransferase and regulates multiple key processes of rice plant development

    New Phytologist, 215:609-623, 2017. | DOI : 10.1111/nph.14596DOI logo

  • PINON V., YAO X., DONG A. and SHEN W.H.

    H3K4me3 is crucial for chromatin condensation and mitotic division during male gametogenesis

    Plant Physiology, 174:1205-1215, 2017. | DOI : 10.1104/pp.17.00306DOI logo

  • HUANG Y., CHEN D.H., LIU B.Y., SHEN W.H. and RUAN Y.

    Conservation and diversification of Polycomb Repressive Complex 2 (PRC2) proteins in the green lineage

    Briefings in Functional Genomics, 16(2):106-119, 2017. | DOI : 10.1093/bfgp/elw007DOI logo

  • LIU B., WEI G., SHI J., JIN J., SHEN T., NI T., SHEN W.H., YU Y. and DONG A.

    SET DOMAIN GROUP 708, a histone H3 lysine 36-specific methyltransferase, controls flowering time in rice.

    New Phytologist, 210(2):577-588, 2016. | DOI : 10.1111/nph.13768DOI logo

  • CHEN D., MOLITOR A., XU L. and SHEN W.H.

    Arabidopsis PRC1 Core Component AtRING1 Regulates Stem Cell-determining Carpel Development mainly through Repression of Class-I KNOX Genes

    BMC Biology, 14:112, 2016. | DOI : 10.1186/s12915-016-0336-4DOI logo

  • WANG H., LIU C., CHENG J., LIU J., ZHANG L., HE C., SHEN W.H., JIN H., XU L. and ZHANG Y.

    Arabidopsis flower and embryo developmental genes are repressed in seedlings by different combinations of Polcomb Group proteins in association with distinct sets of cis-regulatory elements.

    PLoS Genetics, 12(1):e1005771, 2016. | DOI : 10.1371/journal.pgen.1005771DOI logo

  • FENG J., CHEN D., BERR A. and SHEN W.H.

    ZRF1 chromatin regulators have Polycomb-silencing and independent roles in plant development

    Plant Physiology, 172(3):1746-1759, 2016. | DOI : 10.1104/pp.16.00193DOI logo

  • ZHOU W., GAO J., MA J., CAO L., ZHANG C., ZHU Y., DONG A. and SHEN W.H.

    Distinct roles of the histone chaperones NAP1 and NRP and the chromatin-remodeling factor INO80 in somatic homologous recombination in Arabidopsis thaliana

    Plant Journal, 88:397-410, 2016. | DOI : 10.1111/tpj.13256DOI logo

  • LIU B., BERR A., CHANG C., LIU C., SHEN W.H. and RUAN Y.

    Interplay of the histone methyltransferases SDG8 and SDG26 in the regulation of transcription and plant flowering and development

    Biochimica et Biophysica Acta Gene Regulatory Mechanisms, 1859:581-590, 2016. | DOI : 10.1016/j.bbagrm.2016.02.003DOI logo

  • LI Z., LI B., LIU J., GUO Z., LIU Y., LI Y., SHEN W.H., HUANG Y., HUANG H., ZHANG Y. and DONG A.

    Transcription factors AS1 and AS2 interact with LHP1 to repress KNOX genes in Arabidopsis

    Journal of Integrative Plant Biology, 58(12):959-970, 2016. | DOI : 10.1111/jipb.12485DOI logo

  • CHEN D., HUANG Y., RUAN Y. and SHEN W.H.

    The evolutionary landscape of PRC1 core components in green lineage

    Planta, 243(4):825-46, 2016. | DOI : 10.1007/s00425-015-2451-9DOI logo

  • HUANG Y., CHEN D., LIU C., SHEN W.H. and RUAN Y.

    Evolution and conservation of JmjC domain proteins in the green lineage

    Molecular Genetics and Genomics, 291:33-49, 2016. | DOI : 10.1007/s00438-015-1089-4DOI logo

  • BERR A., ZHANG X. and SHEN W.H.

    Réciprocité entre transcription active et méthylation des histones

    Biologie Aujourd’hui, 210(4):269-282, 2016. | DOI : 10.1051/jbio/2017004DOI logo

  • LEE J., YUN J.Y., ZHAO W., SHEN W.H. and AMASINO R.M.

    A methyltransferase required for proper timing of the vernalization response in Arabidopsis

    Proceedings of the National Academy of Sciences of the United States of America, 112(7):2269-2274, 2015. | DOI : 10.1073/pnas.1423585112DOI logo

  • ZHOU W., ZHU Y., DONG A. and SHEN W.H.

    Histone H2A/H2B chaperones: from molecules to chromatin-based functions in plant growth and development.

    Plant Journal, 83:78-95, 2015. | DOI : 10.1111/tpj.12830DOI logo

  • BERR A., SHAFIQ S., PINON V., DONG A. and SHEN W.H.

    The trxG family histone-methyltransferase SET DOMAIN GROUP 26 promotes flowering via a distinctive genetic pathway.

    Plant Journal, 81:316-328, 2015. | DOI : 10.1111/tpj.12729DOI logo

  • ZHANG C., CAO L., RONG L., AN Z., ZHOU W., MA J., SHEN W.H., ZHU Y. and DONG A.

    The chromatin-remodeling factor AtINO80 plays crucial roles in genome stability maintenance and in plant development.

    Plant Journal, 82:655-668, 2015. | DOI : 10.1111/tpj.12840DOI logo

  • SHI J., DONG A. and SHEN W.H.

    Epigenetic regulation of rice flowering and reproduction

    Frontiers in Plant Science, 5(janv 28):803, 2015. | DOI : 10.3389/fpls.2014.00803DOI logo

  • ZHAO W., SHAFIQ S., BERR A. and SHEN W.H.

    Genome-wide gene expression profiling to investigate molecular phenotypes of Arabidopsis mutants deprived in distinct histone methyltransferases and demethylases

    Genomics Data, 4:143-145, 2015. | DOI : 10.1016/j.gdata.2015.04.006DOI logo

  • SHAFIQ S., BERR A. and SHEN W.H.

    Combinatorial functions of diverse histone methylations in Arabidopsis thaliana flowering time regulation

    New Phytologist, 201:312-322, 2014. | DOI : 10.1111/nph.12493DOI logo

  • MOLITOR A.M., BU Z., YU Y. and SHEN W.H.

    Arabidopsis AL PHD-PRC1 complexes promote seed germination through H3K4me3-to-H3K27me3 chromatin state switch in repression of seed developmental genes

    PLoS Genetics, 10(1):e1004091, 2014. | DOI : 10.1371/journal.pgen.1004091DOI logo

  • WENG M., YANG Y., FENG H., PAN Z., SHEN W.H., ZHU Y. and DONG A.

    Histone chaperone ASF1 is involved in gene transcription activation in response to heat stress in Arabidopsis thaliana.

    Plant Cell and Environment, 37(9):2128-38, 2014. | DOI : 10.1111/pce.12299DOI logo

  • FENG J. and SHEN W.H.

    Dynamic regulation and function of histone monoubiquitination in plants.

    Frontiers in Plant Science, 5(83):doi:10.3389/fpls.2014.0083, 2014. | DOI : 10.3389/fpls.2014.00083DOI logo

  • MENARD R., VERDIER G., ORS M., ERHARDT M., BEISSON F. and SHEN W.H.

    Histone H2B monoubiquitination is involved in the regulation of cutin and wax composition in Arabidopsis thaliana

    Plant and Cell Physiology, 55(2):455-466, 2014. | DOI : 10.1093/pcp/pct182DOI logo

  • CHEN D., HUANG Y., LIU C., RUAN Y. and SHEN W.H.

    Functional conservation and divergence of J-domain-containing ZUO1/ZRF orthologs throughout evolution

    Planta, 239:1159-1173, 2014. | DOI : 10.1007/s00425-014-2058-6DOI logo

  • SUI P., SHI J., GAO X., SHEN W.H. and DONG A.

    H3K36 methylation is involved in promoting rice flowering

    Molecular Plant, 6(3):975-977, 2013. | DOI : 10.1093/mp/sss152DOI logo

  • MOES D., GATTI S., HOFFMANN C., DIETERLE M., MOREAU F., NEUMANN K., SCHUMACHER M., DIEDERICH M., GRILL E., SHEN W.H., STEINMETZ A. and THOMAS C.

    A LIM domain protein from Tobacco involved in Actin-Bundling and histone gene transcription

    Molecular Plant, 6(2):483-502, 2013. | DOI : 10.1093/mp/sss075DOI logo

  • MOLITOR A. and SHEN W.H.

    The Polycomb complex PRC1: composition and function in plants.

    Journal of Genetics and Genomics, 40(5):231-238, 2013. | DOI : 10.1016/j.jgg.2012.12.005DOI logo

  • YAO X., FENG H., YU Y., DONG A. and SHEN W.H.

    SDG2-mediated H3K4 methylation is required for proper Arabidopsis root growth and development.

    PLoS ONE, 8(2):e5637, 2013. | DOI : 10.1371/journal.pone.0056537DOI logo

  • GAO J., ZHU Y., ZHOU W., MOLINIER J., DONG A. and SHEN W.H.

    NAP1 Family Histone Chaperones Are Required for Somatic Homologous Recombination in Arabidopsis.

    Plant Cell, 24:1437-1447, 2012. | DOI : 10.1105/tpc.112.096792DOI logo

  • SUI P., JIN J., YE S., MU C., GAO J., FENG H., SHEN W.H., YU Y. and DONG A.

    H3K36 methylation is critical for brassinosteroid-regulated plant growth and development in rice.

    Plant Journal, 70:340-347, 2012. | DOI : 10.1111/j.1365-313X.2011.04873.xDOI logo

  • LI Z., LI B., SHEN W.H., HUANG H. and DONG A.

    TCP transcription factors interact with AS2 in the repression of class-I KNOX genes in Arabidopsis thaliana.

    Plant Journal, 71:99-107, 2012. | DOI : 10.1111/j.1365-313X.2012.04973.xDOI logo

  • ZHU Y., DONG A. and SHEN W.H.

    Histone variants and chromatin assembly in plant abiotic stress responses.

    Biochimica et Biophysica Acta Gene Regulatory Mechanisms, 1819:313-348, 2012. | DOI : 10.1016/j.bbagrm.2011.07.012DOI logo

  • BERR A., MENARD R., HEITZ T. and SHEN W.H.

    Chromatin modification and remodelling: a regulatory landscape for the control of Arabidopsis defence responses upon pathogen attack.

    Cellular Microbiology, 14(6):829-839, 2012. | DOI : 10.1111/j.1462-5822.2012.01785.xDOI logo

  • WIDIEZ T., EL-KAFAFI E.I., GIRIN T., BERR A., RUFFEL S., KROUK G., VAYSSIÈRES A., SHEN W.H., CORUZZI G., GOJON A. and LEPETIT M.

    High Nitrogen Insensitive 9 (HNI9)-mediated systemic repression of root NO3 uptake is assiociated with changes in histone methylation

    Proceedings of the National Academy of Sciences of the United States of America, 108(32):13329-13334, 2011. | DOI : 10.1073/pnas.1017863108DOI logo

  • ZHU Y., WENG M., YANG Y., ZHANG C., LI Z., SHEN W.H. and DONG A.

    Arabidopsis homologues of the histone chaperone ASF1 are crucial for chromatin replication and cell proliferation in plant development

    Plant Journal, 66:443-455, 2011. | DOI : 10.1111/j.1365-313X.2011.04504.xDOI logo

  • BERR A., SHAFIQ S. and SHEN W.H.

    Histone modifications in transcriptional activation during plant development

    Biochimica et Biophysica Acta Gene Regulatory Mechanisms, 1809(10):567-576, 2011. | DOI : 10.1016/j.bbagrm.2011.07.001DOI logo

  • HUANG Y., LIU C., SHEN W.H. and RYUAN Y.

    Phylogenetic analysis and classification of the Brassica rapa SET-domain protein family

    BMC Plant Biology, 11-175, 2011. | DOI : 10.1186/1471-2229-11-175DOI logo

  • YAO X. and SHEN W.H.

    Crucial function of histone lysine methylation in plant reproduction

    Chinese Science Bulletin, 56:3493-3499, 2011. | DOI : 10.1007/s11434-011-4814-3DOI logo

  • BERR A., MCCALLUM E., MENARD R., MEYER D., FUCHS J., DONG A. and SHEN W.H.

    Arabidopsis SET DOMAIN GROUP2 is required for H3K4 trimethylation and is crucial for both sporophyte and gametophyte development.

    Plant Cell, 3232, 2010. | DOI : 10.1105/tpc.110.079962DOI logo