Leader: Valérie COGNAT
The bioinformatics core facility provides bioinformatics services for all IBMP researchers, specially in next generation sequencing data analysis.
The platform has a dedicated server that is open in partnership with GMGM and LNCA.
Account form to request access to the cluster.
The facility has expertise in NGS data analysis, particularly with Illumina and Oxford Nanopore technologies. It covers various topics, including :
– Small genome assembly,
– Transcriptome analysis (RNA-seq and smallRNA-seq)
– 16S metagenomics
– Protein/DNA-RNA interactions (ChIP-seq, …)
– Methylation
Our team collaborate with AEG platform to assist biologist from experimental design to results exploration.
With the SSI team, the bioinformatics provided a dedicated server of 192 cores, 864 Gb RAM and 60 To of working space for the IBMP and partners. Private storage volumes for each institute are available for project storage and backup. Several software tools, in particular for high-throughput data analysis, are deployed on the cluster.
Anyone working in a partner lab can ask an account with the Account form. Other people can contact the platform manager to ask a partnership.
The facility has expertise in programming (R, python, bash, perl) and develops some visualisation tools and databases on request.
Ingénieur de recherche / Research engineer
Ingénieur d'études / Engineer
Ingénieur d'études / Engineer
BÖHRER M., RYMEN B., HIMBER C., GERBAUD A., PFLIEGER D., LAUDENCIA-CHINGCUANCO D., CARTWRIGHT A., VOGEL J., SIBOUT R. and BLEVINS T.
Integrated genome-scale analysis and northern blot detection of retrotransposon siRNAs across plant species
, , 2020.
GOSWAMI R., ASNACIOS A., MILANI P., GRAINDORGE S., HOULNÉ G., HAMANT O. and CHABOUTÉ M.E.
Mechanical shielding in plant nuclei.
Current Biology,
:,
2020.
| DOI : 10.1016/j.cub.2020.03.059
GENTRIC N., MASOUD K., JOURNOT R.P., COGNAT V., CHABOUTÉ M.E., NOIR S. and GENSCHIK P.
The F-box-like protein FBL17 is a regulator of DNA-damage response and co-localizes with RETINOBLASTOMA RELATED 1 at DNA lesion sites
Plant Physiology,
:20.00188,
2020.
| DOI : DOI:10.1104/pp.20.00188
MEGEL C., HUMMEL G., LALANDE S., UBRIG E., COGNAT V., MORELLE G., SALINAS-GIEGÉ T., DUCHÊNE A.M. and MARÉCHAL-DROUARD L.
Plant RNases T2, but not Dicer-like proteins, are major players of tRNA-derived fragments biogenesis
Nucleic Acids Research,
47(2):941-952,
2019.
| DOI : 10.1093/nar/gky1156
LANGE H., NDECKY S., GOMEZ-DIAZ C., PFLIEGER D., BUTEL N., ZUMSTEG J., KUHN L., PIERMARIA C., CHICHER J., CHRISTIE M., KARAASLAN E.S., LANG P.L., WEIGEL D., VAUCHERET H., HAMMANN P. and GAGLIARDI D.
RST1 and RIPR connect the cytosolic RNA exosome to the Ski complex in Arabidopsis
Nature Communications,
10:3871,
2019.
| DOI : 10.1038/s41467-019-11807-4
